Giampaolo Perna is the Principal Investigator of a multi-centric study entitled: “Are Anxiety Disorders associated with accelerated cognitive decline and molecular mechanisms of dementia? a multi-centric italian study in middle-aged and older patients and controls”. The study obtained a grant of 313.870 Euro (2015-2019) from Cariplo Foundation. The centers that will participate are the Italian Province of Sisters Hospitallers - Department of Clinical Neurosciences at Villa San Benedetto Menni (Prof. G. Perna – Dr. D.Caldirola)  & Villa San Giuseppe (Dr. A. Valchera), Scientific Institute IRCCS “E. Medea” -  Udine & Bosisio Parini (prof. P. Brambilla), Department of Neuroscience – Division psychiatry- University of Siena (prof. A. Fagiolini) & Institute of Neuroscience of the National Research Council of Italy at University of Cagliari (Prof. G. Biggio).